Cardiology

Trials, guidelines and practice across cardiovascular medicine.

PRDX3 Loss Linked to Bradyarrhythmia via Ferroptosis and Macrophage Infiltration

Rat and human tissue data connect PRDX3 loss to ferroptosis, inflammatory macrophage infiltration, and worse bradyarrhythmia in the cardiac ganglion plexus.

By Dr. Aishwarya N., MBBS · 2 days ago · 5 min read

Cardiology·STAT

Ionis stock falls after Tryngolza sales outlook is cut sharply

Ionis cut Tryngolza sales guidance after weak third-quarter sales, sending shares down about 25% and erasing more than…

2 days ago

Cardiology·JCI

Cancer Cachexia Triggers Cardiac Wasting in Human iPSC Models

Human iPSC cardiac models link cancer cachexia to AKT/mTORC1 suppression, FOXO activation, autophagy, and persistent contractile dysfunction.

2 days ago

Cardiology·Med Econ

AHA Trials Test Intensive Blood Pressure Targets After Stroke and in Diabetes

AHA trials found a lower systolic goal cut events after stroke, but not in diabetes, with more kidney…

2 days ago

Cardiology·ScienceDaily

Heart attack risk persists despite low LDL, study finds

Proteomics study links TRL and Lp(a) to inflammation and vessel damage, explaining why heart attack risk can persist…

2 days ago

Cardiology·BBC Dental

Scott McTominay had heart procedure days before World Cup match

Scott McTominay underwent treatment for an irregular heartbeat two days before Scotland’s World Cup opener, then returned to…

2 days ago

Cardiology·Modern HC

PhysioNet Review Tracks Cardiology Data Sharing to Foundation Models

A PhysioNet review traces 35 years of cardiology data sharing and outlines open-access, foundation models, and edge AI…

2 days ago

Cardiology·JNCI

Selenium Deficiency and Acute Heart Failure Outcomes in Older Adults

A prospective observational study examines whether selenium deficiency affects clinical outcomes in elderly patients hospitalized with acute heart…

2 days ago

Cardiology·JNCI

Sacubitril/valsartan explored for pediatric radiation-induced heart disease

An abstract on sacubitril/valsartan examines preclinical and clinical findings in children with radiation-induced heart disease, a high-risk late…

2 days ago

Cardiology·EHJ

Biatrial Cardiomyopathy Score Examines Severity in Left-Sided Valvular Disease

A European Heart Journal study examined a composite biatrial cardiomyopathy severity score and its clinical associations in left-sided…

3 days ago

Cardiology

Trials, guidelines and practice across cardiovascular medicine.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.