Cardiology

Trials, guidelines and practice across cardiovascular medicine.

Lipoprotein(a) linked to carotid plaque initiation and stenosis in Suita Study

High lipoprotein(a) tracked with carotid plaque onset, faster IMT progression, and greater stenosis risk in a long-term Japanese cohort.

By Dr. Aishwarya N., MBBS · Oct 22, 2026 · 5 min read

Cardiology·JACC

Hyperaldosteronism Emerges as a Core Driver of CKM Syndrome

Hyperaldosteronism is increasingly recognized as a driver of cardiovascular-kidney-metabolic syndrome, shaping therapy across RAAS blockade and mineralocorticoid antagonism.

Oct 22, 2026

Cardiology·Lancet

Orforglipron shows cardiovascular safety in ACHIEVE-4 diabetes trial

ACHIEVE-4 found oral orforglipron non-inferior to insulin glargine for MACE-4 in high-risk adults with type 2 diabetes.

Oct 22, 2026

Cardiology·medRxiv

Antarctic Cardiovascular Risk Models Disagree in Deployment Screening

In US Antarctic Program candidates, PREVENT and Framingham aligned better than PCE, while advanced screening identified most evacuees…

Oct 22, 2026

Cardiology·medRxiv

Heart rate variability unchanged in Andean workers exposed to intermittent hypoxia

A cross-sectional study found no significant resting heart rate variability or ECG differences in Andean workers exposed to…

Oct 22, 2026

Cardiology·JACC

Upper Extremity Vascular Access Expands in Structural Heart Interventions

Radial and axillary access are gaining ground in structural heart procedures, offering safer alternatives to femoral entry in…

Oct 22, 2026

Cardiology·JACC

Kyrgyz Republic cardiovascular disease burden rose sharply in 2022

National data from Kyrgyz Republic show volatile cardiovascular morbidity from 2018 to 2024, with hypertension, coronary disease and…

Oct 22, 2026

Cardiology·Cancer Cell

Atherosclerosis Review Maps Immune Heterogeneity to Precision Therapy

A review links immune-cell heterogeneity to plaque growth, cap weakening, and thrombosis in atherosclerosis, with implications for precision…

Oct 22, 2026

Cardiology·Nat Rev Neuro

Depression and Disability Raise CVD Risk in CKM Stages 0–3

In adults with early CKM syndrome, depression and functional disability independently raised incident CVD risk and modestly improved…

Oct 22, 2026

Cardiology·ClinicalTrials

PULSE-SED Trial Tests Sedation vs General Anesthesia in AF Ablation

PULSE-SED will compare conscious sedation and general anesthesia during pulsed field ablation for paroxysmal atrial fibrillation in 390…

Oct 22, 2026

Cardiology

Trials, guidelines and practice across cardiovascular medicine.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.