Bioinformatics

Clinical evidence, research, and medical intelligence in Bioinformatics.

CellDiffusion Aims to Improve scRNA-seq Integration and Cell-Cell Inference

CellDiffusion is presented as a method for scRNA-seq data integration, with a focus on more accurate cell-cell association inference in single-cell analysis.

By Dr. A. Nikhil Krishnan, MBBS · Oct 24, 2026 · 5 min read

Bioinformatics·bioRxiv

BioMINTREL boosts biological reasoning with cross-disciplinary AI representations

BioMINTREL linked methods from other fields to biological data, improving expert agreement and surfacing new analyses in preprint…

Oct 21, 2026

Bioinformatics·bioRxiv

MOFI maps multi-omics cell fate progression across time-series data

MOFI integrates RNA, chromatin, and protein snapshots to reconstruct continuous cell fate progression across developmental and perturbation datasets.

Oct 19, 2026

Bioinformatics·bioRxiv

Distributed AI Agents Speed Biological Discovery in Perturb-seq Atlas

A bioRxiv preprint shows distributed AI agents can analyze a whole-brain Perturb-seq atlas in minutes and recover expert-level…

Oct 19, 2026

Bioinformatics·bioRxiv

SMARTFlexDB maps RNA conformational flexibility for small-molecule recognition

SMARTFlexDB pairs apo and holo RNA structures to map conformational change, ligand contacts, and pocket-level flexibility for drug…

Oct 16, 2026

Bioinformatics

Clinical evidence, research, and medical intelligence in Bioinformatics.

In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.