Dr. A. Nikhil Krishnan, MBBS

Active Clinical Contributor & Author

Clinical Articles & Analysis by Dr. A. Nikhil Krishnan, MBBS

3718 Articles

15-PGDH inhibition in osteoarthritis raises cartilage repair hopes and safety questions

A Bone Research review examines 15-PGDH inhibition in osteoarthritis, linking PGE2 skeletal interoception, cartilage repair and compartment-specific risk.

Oct 24, 2026

Orthopedics·Med News Today

Crunching Sound in Neck: Common Causes, Diagnosis, and Care

Neck crunching is often harmless, but pain, stiffness, swelling, or numbness can signal injury, arthritis, or spinal disease.

Oct 24, 2026

Genomics·bioRxiv

Spatial genomics tool maps tumor lineages and cell migration

StarTrak integrates mutations, images, and spatial data to reconstruct cell lineages and migration in tissue sections at single-pixel…

Oct 24, 2026

Sports Medicine·medRxiv

Resistance Training Frequency Shows No Hypertrophy Advantage at Equal Volume

A meta-analysis of 16 trials found no meaningful muscle growth difference between one, two, or three weekly resistance…

Oct 24, 2026

Pulmonology·Nature

3Cs-Based Vaccine Intervention Raises COPD Flu and Pneumococcal Uptake

A 3Cs-based education and prescription strategy lowered vaccine hesitancy and improved influenza and pneumococcal vaccination in COPD patients.

Oct 24, 2026

Orthopedics·Nature

Social alienation model in adolescent idiopathic scoliosis identifies high-risk trajectories

A prospective cohort study in adolescent idiopathic scoliosis identified three social alienation trajectories and a seven-factor prediction model…

Oct 24, 2026

Genetics·Nature

Maternal Age and Trisomy 21 Origin in Libyan Down Syndrome Families

Libyan family data suggest maternal-origin trisomy 21 remains predominant across age groups, but D21S11 tracing was limited and…

Oct 24, 2026

Nursing·NLM Alerts

Peripheral IV Therapy Complications: Edema, Air Embolism, CR-BSI

Peripheral IV therapy can trigger pulmonary edema, air embolism, catheter embolism, and CR-BSI. Early recognition and prevention are…

Oct 24, 2026

Dermatology·ClinicalTrials

Nail Psoriasis Trial Tests Intralesional Methotrexate vs Triamcinolone

A phase 2 left-right study in nail psoriasis compares intralesional methotrexate and triamcinolone acetonide by NAPSI, ultrasound, and…

Oct 24, 2026

Hepatology·ClinicalTrials

Kylo-0603 Phase 2a Trial Targets MASLD Liver Fat Reduction

A Phase 2a study will test once-daily Kylo-0603 in MASLD, with MRI-PDFF liver fat change at 12 weeks…

Oct 24, 2026

Independent Review Board

All articles authored by our clinical fellows are cross-audited by MWF Review Team featuring 10 senior department chairs from premier hospitals.

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In Brief The 5-minute rounds

New hypertension guideline lowers the treatment threshold to 130/80 mm Hg.
Phase 3 GLP-1 trial reports a 20% cut in major adverse cardiac events.
FDA clears a next-generation CAR-T therapy for relapsed lymphoma.
Meta-analysis links early mobilisation to shorter ICU length of stay.
Rapid guidance broadens empiric antibiotics for suspected sepsis.